Large epidemiological studies (studies that deal with incidence, distribution and control of disease in a population), demonstrate that people with an affected first-degree relative, such as a parent or sibling, have a two-to-three fold increased risk of developing Parkinson's, as compared to the general population.
Scientists have identified 13 genes that are associated with Parkinson’s and can cause the disease in a small number of families.
The genes identified to date include: PARK1, DJ-1 (PARK7), Pink1 (Park6), dardarin (DRDN), Tau, lrrk2, parkin, uchl-1, park3, park9, park10, park11. |